COVID-19 Single Cell and Spatial Lung Atlas

We generated an integrated sc/snRNA-seq object comprising our own snRNA-seq data and 12 publicly available sc/snRNA-seq datasets.

Organ donor (n=89) lung samples were used as control in comparison with COVID-19 (n=51) tissue.

The resulting integrated object comprises 536k cells and nuclei with 32 distinct cell states across epithelial, endothelial, fibroblast, B cell, myeloid and lymphoid, including T cell compartments.